Interesting just how little this matters to San Francisco (they'd need to put a wall around SFO, OAK, and maybe SJC, and not sure about the parts of Mountain View and Menlo Park where tech offices are).
Unfortunate that DC doesn't have more flooding planned.
At 25 feet, it looks like the shoreline moves up (at least) to highway 101, but that map doesn't go far enough south to really be sure. Look at this and you can really see the impact: http://cal-adapt.org/sealevel/
Just at a glance, I'd write off Oracle, Facebook, Google, Yahoo, Moffett, Alviso, the new 49ers stadium, lots of Cisco buildings around Tasman, and that industrial park up in Fremont where they shot the T2 Cyberdyne office scenes. The inundation of the SJ/SC water treatment plant would also make things even worse, I imagine.
For SF proper, most neighborhoods would be relatively little affected on account of hills, though there are significant amounts of the city built on bay fill or low-lying land, particularly the Marina, parts of downtown, SOMA, and Hunters Point. Around the rest of the bay, communities/developments on the bay itself (especially on the bay side of major highways) are more likely to be on fill and subject to rising sea levels. This includes major office parks in various parts of the bay, including much of the North First Street area of San Jose, the GooglePlex, Oyster Point, Emeryville, Hayward, and Fremont.
As the maps make clear, the real hazard is in the Delta and Central Valley. Prior to modern flood control (dams and levees), much of the Central Valley was effectively an inland sea through the winter and spring. Rising sea levels would put much of the existing (and already threatened) levee system at risk. Sacramento, Stockton, and other communities would be substantially affected.
Unfortunate that DC doesn't have more flooding planned.